2ath

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Image:2ath.png

Template:STRUCTURE 2ath

Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist

Template:ABSTRACT PUBMED 16366601

About this Structure

2ATH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mahindroo N, Huang CF, Peng YH, Wang CC, Liao CC, Lien TW, Chittimalla SK, Huang WJ, Chai CH, Prakash E, Chen CP, Hsu TA, Peng CH, Lu IL, Lee LH, Chang YW, Chen WC, Chou YC, Chen CT, Goparaju CM, Chen YS, Lan SJ, Yu MC, Chen X, Chao YS, Wu SY, Hsieh HP. Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities. J Med Chem. 2005 Dec 29;48(26):8194-208. PMID:16366601 doi:10.1021/jm0506930

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