2r7g

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Image:2r7g.png

Template:STRUCTURE 2r7g

Contents

Structure of the retinoblastoma protein pocket domain in complex with adenovirus E1A CR1 domain

Template:ABSTRACT PUBMED 17974914

Disease

Known disease associated with this structure: Bladder cancer OMIM:[180200], Osteosarcoma OMIM:[180200], Pinealoma with bilateral retinoblastoma OMIM:[180200], Retinoblastoma OMIM:[180200]

About this Structure

2R7G is a 5 chains structure of sequences from Homo sapiens and Human adenovirus 5. Full crystallographic information is available from OCA.

Reference

  • Liu X, Marmorstein R. Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev. 2007 Nov 1;21(21):2711-6. PMID:17974914 doi:21/21/2711

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