1t2v

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Template:STRUCTURE 1t2v

Contents

Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide

Template:ABSTRACT PUBMED 15133503

Disease

Known disease associated with this structure: Breast cancer-1 OMIM:[113705], Breast-ovarian cancer OMIM:[113705], Ovarian cancer OMIM:[113705], Papillary serous carcinoma of the peritoneum OMIM:[113705]

About this Structure

1T2V is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:http://dx.doi.org/10.1038/nsmb776

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