1s19

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Template:STRUCTURE 1s19

Crystal structure of VDR ligand binding domain complexed to calcipotriol.

Template:ABSTRACT PUBMED 15055995

About this Structure

1S19 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D. Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J Med Chem. 2004 Apr 8;47(8):1956-61. PMID:15055995 doi:10.1021/jm0310582

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