2ien
From Proteopedia
Crystal structure analysis of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017)
Template:ABSTRACT PUBMED 15066436
About this Structure
2IEN is a 2 chains structure of sequences from Human immunodeficiency virus 1. This structure supersedes the now removed PDB entry 1s6g. Full crystallographic information is available from OCA.
Reference
- Tie Y, Boross PI, Wang YF, Gaddis L, Hussain AK, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains. J Mol Biol. 2004 Apr 23;338(2):341-52. PMID:15066436 doi:10.1016/j.jmb.2004.02.052
- Koh Y, Nakata H, Maeda K, Ogata H, Bilcer G, Devasamudram T, Kincaid JF, Boross P, Wang YF, Tie Y, Volarath P, Gaddis L, Harrison RW, Weber IT, Ghosh AK, Mitsuya H. Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro. Antimicrob Agents Chemother. 2003 Oct;47(10):3123-9. PMID:14506019
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