1qbs

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Image:1qbs.png

Template:STRUCTURE 1qbs

HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY

Template:ABSTRACT PUBMED 8784449

About this Structure

1QBS is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Lam PY, Ru Y, Jadhav PK, Aldrich PE, DeLucca GV, Eyermann CJ, Chang CH, Emmett G, Holler ER, Daneker WF, Li L, Confalone PN, McHugh RJ, Han Q, Li R, Markwalder JA, Seitz SP, Sharpe TR, Bacheler LT, Rayner MM, Klabe RM, Shum L, Winslow DL, Kornhauser DM, Hodge CN, et al.. Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas. J Med Chem. 1996 Aug 30;39(18):3514-25. PMID:8784449 doi:10.1021/jm9602571

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