1m4u

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Template:STRUCTURE 1m4u

Contents

Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin

Template:ABSTRACT PUBMED 12478285

Disease

Known disease associated with this structure: Stapes ankylosis syndrome without symphalangism OMIM:[602991], Symphalangism, proximal OMIM:[602991], Synostoses syndrome, multiple, 1 OMIM:[602991], Tarsal-carpal coalition syndrome OMIM:[602991]

About this Structure

1M4U is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Belmonte JC, Choe S. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 2002 Dec 12;420(6916):636-42. PMID:12478285 doi:10.1038/nature01245

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