1bq1

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Template:STRUCTURE 1bq1

E. COLI THYMIDYLATE SYNTHASE MUTANT N177A IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)

Template:ABSTRACT PUBMED 9826509

About this Structure

1BQ1 is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Reyes CL, Sage CR, Rutenber EE, Nissen RM, Finer-Moore JS, Stroud RM. Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer. J Mol Biol. 1998 Dec 4;284(3):699-712. PMID:9826509 doi:http://dx.doi.org/10.1006/jmbi.1998.2205

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