3c6m

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Image:3c6m.png

Template:STRUCTURE 3c6m

Contents

Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine

Template:ABSTRACT PUBMED 18367445

Disease

Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[300105], Smith-Magenis syndrome OMIM:[607642]

About this Structure

3C6M is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wu H, Min J, Zeng H, McCloskey DE, Ikeguchi Y, Loppnau P, Michael AJ, Pegg AE, Plotnikov AN. Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism. J Biol Chem. 2008 Jun 6;283(23):16135-46. Epub 2008 Mar 26. PMID:18367445 doi:http://dx.doi.org/10.1074/jbc.M710323200

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