1tsn

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Template:STRUCTURE 1tsn

THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH FDUMP AND METHYLENETETRAHYDROFOLATE

Template:ABSTRACT PUBMED 9109668

About this Structure

1TSN is a 1 chain structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Hyatt DC, Maley F, Montfort WR. Use of strain in a stereospecific catalytic mechanism: crystal structures of Escherichia coli thymidylate synthase bound to FdUMP and methylenetetrahydrofolate. Biochemistry. 1997 Apr 15;36(15):4585-94. PMID:9109668 doi:10.1021/bi962936j

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