1zsa

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Image:1zsa.png

Template:STRUCTURE 1zsa

Contents

CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM

Template:ABSTRACT PUBMED 8639494

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

1ZSA is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Huang, CC, Lesburg CA, Kiefer LL, Fierke CA, Christianson DW. Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry. 1996 Mar 19;35(11):3439-46. PMID:8639494 doi:10.1021/bi9526692

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