1o0d

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Template:STRUCTURE 1o0d

Contents 1 Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor 2 Disease 3 About this Structure 4 Reference

Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor

Template:ABSTRACT PUBMED 12781189

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1O0D is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Lange UE, Baucke D, Hornberger W, Mack H, Seitz W, Hoffken HW. D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2029-33. PMID:12781189

Page seeded by OCA on Tue Feb 17 07:07:09 2009