2c1b

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Image:2c1b.png

Template:STRUCTURE 2c1b

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE

Template:ABSTRACT PUBMED 16249095

About this Structure

2C1B is a 2 chains structure of sequences from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Collins I, Caldwell J, Fonseca T, Donald A, Bavetsias V, Hunter LJ, Garrett MD, Rowlands MG, Aherne GW, Davies TG, Berdini V, Woodhead SJ, Davis D, Seavers LC, Wyatt PG, Workman P, McDonald E. Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B. Bioorg Med Chem. 2006 Feb 15;14(4):1255-73. Epub 2005 Oct 24. PMID:16249095 doi:http://dx.doi.org/10.1016/j.bmc.2005.09.055

Page seeded by OCA on Tue Feb 17 07:08:04 2009

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