1upj

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Image:1upj.png

Template:STRUCTURE 1upj

HIV-1 PROTEASE COMPLEX WITH U095438 [3-[1-(4-BROMOPHENYL) ISOBUTYL]-4-HYDROXYCOUMARIN

Template:ABSTRACT PUBMED 7658450

About this Structure

1UPJ is a 1 chain structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Thaisrivongs S, Watenpaugh KD, Howe WJ, Tomich PK, Dolak LA, Chong KT, Tomich CC, Tomasselli AG, Turner SR, Strohbach JW, et al.. Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J Med Chem. 1995 Sep 1;38(18):3624-37. PMID:7658450

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