2i47

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Image:2i47.png

Template:STRUCTURE 2i47

Crystal structure of catalytic domain of TACE with inhibitor

Template:ABSTRACT PUBMED 17064892

About this Structure

2I47 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Condon JS, Joseph-McCarthy D, Levin JI, Lombart HG, Lovering FE, Sun L, Wang W, Xu W, Zhang Y. Identification of potent and selective TACE inhibitors via the S1 pocket. Bioorg Med Chem Lett. 2007 Jan 1;17(1):34-9. Epub 2006 Oct 5. PMID:17064892 doi:10.1016/j.bmcl.2006.10.004

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