1pj2

From Proteopedia

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Template:STRUCTURE 1pj2

Contents 1 Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate 2 Disease 3 About this Structure 4 Reference

Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate

Template:ABSTRACT PUBMED 12962632

Disease

Known disease associated with this structure: Epilepsy, idopathic generalized, susceptibility to OMIM:[154270]

About this Structure

1PJ2 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Tao X, Yang Z, Tong L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure. 2003 Sep;11(9):1141-50. PMID:12962632

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