2hcr

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Image:2hcr.png

Template:STRUCTURE 2hcr

Contents

crystal structure of human phosphoribosyl pyrophosphate synthetase 1 in complex with AMP(ATP), cadmium and sulfate ion

Template:ABSTRACT PUBMED 16939420

Disease

Known disease associated with this structure: Arts syndrome OMIM:[311850], Charcot-Marie-Tooth disease, X-linked recessive, 5 OMIM:[311850], Gout, PRPS-related OMIM:[311850], Phosphoribosylpyrophosphate synthetase superactivity OMIM:[311850]

About this Structure

2HCR is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li S, Lu Y, Peng B, Ding J. Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site. Biochem J. 2007 Jan 1;401(1):39-47. PMID:16939420 doi:10.1042/BJ20061066

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