1u5m

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Template:STRUCTURE 1u5m

Contents

Structure of a Chordin-like Cysteine-rich Repeat (VWC module) from Collagen IIA

Template:ABSTRACT PUBMED 15466413

Disease

Known disease associated with this structure: Achondrogenesis-hypochondrogenesis, type II OMIM:[120140], Epiphyseal dysplasia, multiple, with myopia and deafness OMIM:[120140], Kniest dysplasia OMIM:[120140], Osteoarthrosis OMIM:[120140], SED congenita OMIM:[120140], SED, Namaqualand type OMIM:[120140], SMED Strudwick type OMIM:[120140], Spondyloperipheral dysplasia OMIM:[120140], Stickler syndrome, type I OMIM:[120140], Vitreoretinopathy with phalangeal epiphyseal dysplasia ( OMIM:[120140]

About this Structure

1U5M is a 1 chain structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • O'Leary JM, Hamilton JM, Deane CM, Valeyev NV, Sandell LJ, Downing AK. Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA. J Biol Chem. 2004 Dec 17;279(51):53857-66. Epub 2004 Oct 1. PMID:15466413 doi:http://dx.doi.org/10.1074/jbc.M409225200

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