2ra0

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Image:2ra0.png

Template:STRUCTURE 2ra0

Contents

X-ray Structure of FXa in complex with 7-fluoroindazole

Template:ABSTRACT PUBMED 18159923

Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

2RA0 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lee YK, Parks DJ, Lu T, Thieu TV, Markotan T, Pan W, McComsey DF, Milkiewicz KL, Crysler CS, Ninan N, Abad MC, Giardino EC, Maryanoff BE, Damiano BP, Player MR. 7-fluoroindazoles as potent and selective inhibitors of factor Xa. J Med Chem. 2008 Jan 24;51(2):282-97. Epub 2007 Dec 27. PMID:18159923 doi:10.1021/jm701217r

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