1ozt

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Image:1ozt.png

Template:STRUCTURE 1ozt

Contents

Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution

Template:ABSTRACT PUBMED 12754496

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]

About this Structure

1OZT is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Elam JS, Taylor AB, Strange R, Antonyuk S, Doucette PA, Rodriguez JA, Hasnain SS, Hayward LJ, Valentine JS, Yeates TO, Hart PJ. Amyloid-like filaments and water-filled nanotubes formed by SOD1 mutant proteins linked to familial ALS. Nat Struct Biol. 2003 Jun;10(6):461-7. PMID:12754496 doi:10.1038/nsb935

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