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2iok

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Image:2iok.png

Template:STRUCTURE 2iok

Human estrogen receptor alpha ligand-binding domain in complex with compound 1D

Template:ABSTRACT PUBMED 17289385

About this Structure

2IOK is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dykstra KD, Guo L, Birzin ET, Chan W, Yang YT, Hayes EC, DaSilva CA, Pai LY, Mosley RT, Kraker B, Fitzgerald PM, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2322-8. Epub 2007 Jan 25. PMID:17289385 doi:10.1016/j.bmcl.2007.01.054

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