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2hl4

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Revision as of 08:04, 17 February 2009 by OCA (Talk | contribs)
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Image:2hl4.png

Template:STRUCTURE 2hl4

Crystal structure analysis of human carbonic anhydrase II in complex with a benzenesulfonamide derivative

Template:ABSTRACT PUBMED 17251017

About this Structure

2HL4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Di Fiore A, Scozzafava A, Winum JY, Montero JL, Pedone C, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1726-31. Epub 2007 Jan 8. PMID:17251017 doi:10.1016/j.bmcl.2006.12.099
  • Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406

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