1hvy
From Proteopedia
| |||||||||
| 1hvy, resolution 1.90Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Thymidylate synthase, with EC number 2.1.1.45 | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
Template:ABSTRACT PUBMED 11329255
About this Structure
1HVY is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L. Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. Biochemistry. 2001 Feb 20;40(7):1897-902. PMID:11329255
Page seeded by OCA on Tue Feb 17 10:07:31 2009
