2g50

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Template:STRUCTURE 2g50

The location of the allosteric amino acid binding site of muscle pyruvate kinase.

Template:ABSTRACT PUBMED 16634623

About this Structure

2G50 is a 8 chains structure of sequences from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Williams R, Holyoak T, McDonald G, Gui C, Fenton AW. Differentiating a ligand's chemical requirements for allosteric interactions from those for protein binding. Phenylalanine inhibition of pyruvate kinase. Biochemistry. 2006 May 2;45(17):5421-9. PMID:16634623 doi:10.1021/bi0524262

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