1rkc

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Image:1rkc.png

Template:STRUCTURE 1rkc

Contents

Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)

Template:ABSTRACT PUBMED 14702644

Disease

Known disease associated with this structure: Cardiomyopathy, dilated, 1W OMIM:[193065]

About this Structure

1RKC is a 2 chains structure of sequences from Gallus gallus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Izard T, Evans G, Borgon RA, Rush CL, Bricogne G, Bois PR. Vinculin activation by talin through helical bundle conversion. Nature. 2004 Jan 8;427(6970):171-5. Epub 2003 Dec 31. PMID:14702644 doi:http://dx.doi.org/10.1038/nature02281

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