Template:STRUCTURE 1h2l

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1h2l, resolution 2.25Å ()

Sites:

Ligands:

, ,

Domains:

Cupin_4, HIF-1a_CTAD

Structural annotation:
Resources:	InterPro : Ipr003347, Ipr001092, Ipr001321, Ipr001610, Ipr000014, Ipr011598, Ipr013655, Ipr014887, Ipr000700 Pfam : PF08778 SCOP : d1h2la_, d1h2ls_ UniProt : Q9NWT6, Q16665

Functional annotation:
Resources:	GeneCard : HIF1AN, HIF1A
Cellular component:	nucleus cytoplasm
Biological process:	regulation of transcription, DNA-dependent transcription response to stress positive regulation of transcription response to hypoxia homeostatic process signal transduction transcription, DNA-dependent regulation of transcription
Molecular function:	peptide-aspartate beta-dioxygenase activity iron ion binding oxidoreductase activity metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen protein binding signal transducer activity transcription regulator activity RNA polymerase II transcription factor activity, enhancer binding protein heterodimerization activity transcription factor activity DNA binding histone acetyltransferase binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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