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3cg2

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Template:STRUCTURE 3cg2

P38 Alpha Kinase complexed with a Pyrazolo-Pyrimidine based inhibitor

Template:ABSTRACT PUBMED 18359226

About this Structure

3CG2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Das J, Moquin RV, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly K, Doweyko AM, Sack JS, Zhang H, Kiefer SE, Kish K, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2652-7. Epub 2008 Mar 10. PMID:18359226 doi:10.1016/j.bmcl.2008.03.019

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