1tk8

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Template:STRUCTURE 1tk8

T7 DNA polymerase ternary complex with 8 oxo guanosine and dAMP at the elongation site

Template:ABSTRACT PUBMED 15297882

About this Structure

1TK8 is a 4 chains structure of sequences from Enterobacteria phage t7 and Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Brieba LG, Eichman BF, Kokoska RJ, Doublie S, Kunkel TA, Ellenberger T. Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. EMBO J. 2004 Sep 1;23(17):3452-61. Epub 2004 Aug 5. PMID:15297882 doi:10.1038/sj.emboj.7600354

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