1ms6

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Template:STRUCTURE 1ms6

Dipeptide Nitrile Inhibitor Bound to Cathepsin S.

Template:ABSTRACT PUBMED 12459015

About this Structure

1MS6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ward YD, Thomson DS, Frye LL, Cywin CL, Morwick T, Emmanuel MJ, Zindell R, McNeil D, Bekkali Y, Girardot M, Hrapchak M, DeTuri M, Crane K, White D, Pav S, Wang Y, Hao MH, Grygon CA, Labadia ME, Freeman DM, Davidson W, Hopkins JL, Brown ML, Spero DM. Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors. J Med Chem. 2002 Dec 5;45(25):5471-82. PMID:12459015

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