1nql

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Image:1nql.png

Template:STRUCTURE 1nql

Contents

Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.

Template:ABSTRACT PUBMED 12620237

Disease

Known disease associated with this structure: Hypomagnesemia 4, renal OMIM:[131530]

About this Structure

1NQL is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell. 2003 Feb;11(2):507-17. PMID:12620237

Page seeded by OCA on Tue Feb 17 11:35:32 2009

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