2uzt
From Proteopedia
PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS
Template:ABSTRACT PUBMED 17523610
About this Structure
2UZT is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Zhu GD, Gandhi VB, Gong J, Thomas S, Woods KW, Song X, Li T, Diebold RB, Luo Y, Liu X, Guan R, Klinghofer V, Johnson EF, Bouska J, Olson A, Marsh KC, Stoll VS, Mamo M, Polakowski J, Campbell TJ, Martin RL, Gintant GA, Penning TD, Li Q, Rosenberg SH, Giranda VL. Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase b/akt inhibitors with reduced hypotension. J Med Chem. 2007 Jun 28;50(13):2990-3003. Epub 2007 May 25. PMID:17523610 doi:10.1021/jm0701019
Page seeded by OCA on Tue Feb 17 12:07:31 2009
Categories: Bos taurus | CAMP-dependent protein kinase | Bouska, J. | Campbell, T J. | Diebold, R B. | Gandhi, V B. | Giranda, V L. | Gong, J. | Guan, R. | Johnson, E F. | Klinghofer, V. | Li, Q. | Li, T. | Liu, X. | Luo, Y. | Mamo, M. | Marsh, K C. | Olson, A. | Penning, T D. | Polakowski, J. | Rosenberg, S H. | Song, X. | Stoll, V S. | Thomas, S. | Woods, K W. | Zhu, G D. | Akt inhibitor | Atp-binding | Camp | Kinase | Lipoprotein | Myristate | Nuclear protein | Nucleotide-binding | Phosphorylation | Protein kinase some | Protein kinase inhibitor | Serine/threonine-protein kinase | Transferase
