2vvn

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Image:2vvn.png

Template:STRUCTURE 2vvn

BTGH84 IN COMPLEX WITH NH-BUTYLTHIAZOLINE

Template:ABSTRACT PUBMED 18587388

About this Structure

2VVN is a 2 chains structure of sequences from Bacteroides thetaiotaomicron. Full crystallographic information is available from OCA.

Reference

  • Yuzwa SA, Macauley MS, Heinonen JE, Shan X, Dennis RJ, He Y, Whitworth GE, Stubbs KA, McEachern EJ, Davies GJ, Vocadlo DJ. A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat Chem Biol. 2008 Aug;4(8):483-90. Epub 2008 Jun 29. PMID:18587388 doi:http://dx.doi.org/10.1038/nchembio.96

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