2bq6

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Image:2bq6.png

Template:STRUCTURE 2bq6

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 21

Template:ABSTRACT PUBMED 15999990

About this Structure

2BQ6 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nazare M, Will DW, Matter H, Schreuder H, Ritter K, Urmann M, Essrich M, Bauer A, Wagner M, Czech J, Lorenz M, Laux V, Wehner V. Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography. J Med Chem. 2005 Jul 14;48(14):4511-25. PMID:15999990 doi:http://dx.doi.org/10.1021/jm0490540

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