1eat

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Image:1eat.png

Template:STRUCTURE 1eat

NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 5. DESIGN, SYNTHESIS, AND X-RAY CRYSTALLOGRAPHY OF A SERIES OF ORALLY ACTIVE 5-AMINO-PYRIMIDIN-6-ONE-CONTAINING TRIFLUOROMETHYLKETONES

Template:ABSTRACT PUBMED 7837246

About this Structure

1EAT is a 1 chain structure of sequence from Sus scrofa. Full crystallographic information is available from OCA.

Reference

  • Veale CA, Bernstein PR, Bryant C, Ceccarelli C, Damewood JR Jr, Earley R, Feeney SW, Gomes B, Kosmider BJ, Steelman GB, et al.. Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6-one-containing trifluoromethyl ketones. J Med Chem. 1995 Jan 6;38(1):98-108. PMID:7837246

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