2aze

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Template:STRUCTURE 2aze

Contents 1 Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer 2 Disease 3 About this Structure 4 Reference

Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer

Template:ABSTRACT PUBMED 16360038

Disease

Known disease associated with this structure: Bladder cancer OMIM:[180200], Osteosarcoma OMIM:[180200], Pinealoma with bilateral retinoblastoma OMIM:[180200], Retinoblastoma OMIM:[180200]

About this Structure

2AZE is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Rubin SM, Gall AL, Zheng N, Pavletich NP. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell. 2005 Dec 16;123(6):1093-106. PMID:16360038 doi:10.1016/j.cell.2005.09.044

Page seeded by OCA on Tue Feb 17 13:17:28 2009