2cgo

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Template:STRUCTURE 2cgo

FACTOR INHIBITING HIF-1 ALPHA WITH FUMARATE

Template:ABSTRACT PUBMED 17135241

About this Structure

2CGO is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hewitson KS, Lienard BM, McDonough MA, Clifton IJ, Butler D, Soares AS, Oldham NJ, McNeill LA, Schofield CJ. Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates. J Biol Chem. 2007 Feb 2;282(5):3293-301. Epub 2006 Nov 29. PMID:17135241 doi:10.1074/jbc.M608337200

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