3bv3

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Image:3bv3.png

Template:STRUCTURE 3bv3

Morpholino pyrrolotriazine P38 Alpha Map Kinase inhibitor compound 2

Template:ABSTRACT PUBMED 18364256

About this Structure

3BV3 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wrobleski ST, Lin S, Hynes J Jr, Wu H, Pitt S, Shen DR, Zhang R, Gillooly KM, Shuster DJ, McIntyre KW, Doweyko AM, Kish KF, Tredup JA, Duke GJ, Sack JS, McKinnon M, Dodd J, Barrish JC, Schieven GL, Leftheris K. Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38 alpha MAP kinase inhibitors. Bioorg Med Chem Lett. 2008 Apr 15;18(8):2739-44. Epub 2008 Mar 4. PMID:18364256 doi:10.1016/j.bmcl.2008.02.067

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