2qi8

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Image:2qi8.png

Template:STRUCTURE 2qi8

Crystal structure of drug resistant SRC kinase domain

Template:ABSTRACT PUBMED 18316192

About this Structure

2QI8 is a 2 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053

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