2b5i

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Image:2b5i.png

Template:STRUCTURE 2b5i

Contents

cytokine receptor complex

Template:ABSTRACT PUBMED 16293754

Disease

Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[147730]

About this Structure

2B5I is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang X, Rickert M, Garcia KC. Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors. Science. 2005 Nov 18;310(5751):1159-63. PMID:16293754 doi:310/5751/1159

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