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2dxm

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Image:2dxm.png

Template:STRUCTURE 2dxm

Contents

Neutron Structure Analysis of Deoxy Human Hemoglobin

Template:ABSTRACT PUBMED 17990881

Disease

Known disease associated with this structure: Erythremias, beta- OMIM:[141900], Heinz body anemias, beta- OMIM:[141900], Hereditary persistence of fetal hemoglobin OMIM:[141900], Methemoglobinemias, beta- OMIM:[141900], Sickle cell anemia OMIM:[141900], Thalassemia-beta, dominant inclusion-body OMIM:[141900], Thalassemias, beta- OMIM:[141900]

About this Structure

2DXM is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chatake T, Shibayama N, Park SY, Kurihara K, Tamada T, Tanaka I, Niimura N, Kuroki R, Morimoto Y. Protonation states of buried histidine residues in human deoxyhemoglobin revealed by neutron crystallography. J Am Chem Soc. 2007 Dec 5;129(48):14840-1. Epub 2007 Nov 9. PMID:17990881 doi:10.1021/ja0749441

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