1y98

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Image:1y98.png

Template:STRUCTURE 1y98

Contents

Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.

Template:ABSTRACT PUBMED 16101277

Disease

Known disease associated with this structure: Breast cancer-1 OMIM:[113705], Breast-ovarian cancer OMIM:[113705], Ovarian cancer OMIM:[113705], Papillary serous carcinoma of the peritoneum OMIM:[113705]

About this Structure

1Y98 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Varma AK, Brown RS, Birrane G, Ladias JA. Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry. 2005 Aug 23;44(33):10941-6. PMID:16101277 doi:10.1021/bi0509651

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