2p4a

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Template:STRUCTURE 2p4a

X-ray structure of a camelid affinity matured single-domain vhh antibody fragment in complex with RNASE A

Template:ABSTRACT PUBMED 17888451

About this Structure

2P4A is a 4 chains structure of sequences from Bos taurus and Camelus dromedarius. Full crystallographic information is available from OCA.

Reference

  • Koide A, Tereshko V, Uysal S, Margalef K, Kossiakoff AA, Koide S. Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope. J Mol Biol. 2007 Nov 2;373(4):941-53. Epub 2007 Aug 21. PMID:17888451 doi:10.1016/j.jmb.2007.08.027

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