3dok

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Image:3dok.png

Template:STRUCTURE 3dok

Crystal structure of K103N mutant HIV-1 reverse transcriptase in complex with GW678248.

Template:ABSTRACT PUBMED 18665583

About this Structure

3DOK is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Ren J, Chamberlain PP, Stamp A, Short SA, Weaver KL, Romines KR, Hazen R, Freeman A, Ferris RG, Andrews CW, Boone L, Chan JH, Stammers DK. Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J Med Chem. 2008 Aug 28;51(16):5000-8. Epub 2008 Jul 30. PMID:18665583 doi:10.1021/jm8004493

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