2vc2

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Image:2vc2.png

Template:STRUCTURE 2vc2

RE-REFINEMENT OF INTEGRIN ALPHAIIBBETA3 HEADPIECE BOUND TO ANTAGONIST L-739758

About this Structure

2VC2 is a 4 chains structure of sequences from Homo sapiens and Mus musculus. This structure supersedes the now removed PDB entry 1ty7. Full crystallographic information is available from OCA.

Reference

  • Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004 Nov 4;432(7013):59-67. Epub 2004 Sep 19. PMID:15378069 doi:http://dx.doi.org/10.1038/nature02976

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