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1g49

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Template:STRUCTURE 1g49

Contents

A CARBOXYLIC ACID BASED INHIBITOR IN COMPLEX WITH MMP3

Template:ABSTRACT PUBMED 11150165

Disease

Known disease associated with this structure: Coronary heart disease, susceptibility to, 6 OMIM:[185250]

About this Structure

1G49 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Natchus MG, Bookland RG, De B, Almstead NG, Pikul S, Janusz MJ, Heitmeyer SA, Hookfin EB, Hsieh LC, Dowty ME, Dietsch CR, Patel VS, Garver SM, Gu F, Pokross ME, Mieling GE, Baker TR, Foltz DJ, Peng SX, Bornes DM, Strojnowski MJ, Taiwo YO. Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines. J Med Chem. 2000 Dec 28;43(26):4948-63. PMID:11150165

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