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2k05
From Proteopedia
Contents |
Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21
Template:ABSTRACT PUBMED 18799424
Disease
Known disease associated with this structure: Myelokathexis, isolated OMIM:[162643], WHIM syndrome OMIM:[162643]
About this Structure
2K05 is a 4 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.
Reference
- Veldkamp CT, Seibert C, Peterson FC, De la Cruz NB, Haugner JC 3rd, Basnet H, Sakmar TP, Volkman BF. Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12. Sci Signal. 2008 Sep 16;1(37):ra4. PMID:18799424 doi:1/37/ra4
Page seeded by OCA on Tue Feb 17 17:34:33 2009
Categories: Homo sapiens | Peterson, F C. | Veldkamp, C T. | Volkman, B F. | Alternative splicing | Chemokine | Chemotaxis | Cxcl12 | Cxcr4 | Cytokine | G-protein coupled receptor | Glycoprotein | Growth factor | Host-virus interaction | Locked dimer | Membrane | Receptor | Sdf1-alpha | Secreted | Stromal cell derived factor-1 | Sulfation | Sulfotyrosine | Transducer | Transmembrane
