1qxw

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Image:1qxw.png

Template:STRUCTURE 1qxw

Crystal structure of Staphyloccocus aureus in complex with an aminoketone inhibitor 54135.

Template:ABSTRACT PUBMED 14998322

About this Structure

1QXW is a 1 chain structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Douangamath A, Dale GE, D'Arcy A, Almstetter M, Eckl R, Frutos-Hoener A, Henkel B, Illgen K, Nerdinger S, Schulz H, Mac Sweeney A, Thormann M, Treml A, Pierau S, Wadman S, Oefner C. Crystal structures of Staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate. J Med Chem. 2004 Mar 11;47(6):1325-8. PMID:14998322 doi:http://dx.doi.org/10.1021/jm034188j

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