2fy4

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Image:2fy4.png

Template:STRUCTURE 2fy4

Contents

Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis

Template:ABSTRACT PUBMED 17144655

Disease

Known disease associated with this structure: Myasthenic syndrome, congenital, associated with episodic apnea OMIM:[118490]

About this Structure

2FY4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kim AR, Rylett RJ, Shilton BH. Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry. 2006 Dec 12;45(49):14621-31. PMID:17144655 doi:10.1021/bi061536l

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