Template:STRUCTURE 2fkl

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2fkl, resolution 2.50Å ()

Gene:

APP (Homo sapiens)

Domains:

Related:

1owt, 2fjz, 2fk1, 2fk2, 2fk3

Structural annotation:
Resources:	InterPro : Ipr008154, Ipr013803, Ipr015849, Ipr011178, Ipr002223, Ipr008155 Pfam : PF02177 UniProt : P05067

Functional annotation:
Cellular component:	coated pit extracellular region integral to plasma membrane integral to membrane membrane cell surface
Biological process:	cell adhesion neuromuscular process apoptosis cellular copper ion homeostasis endocytosis Notch signaling pathway
Molecular function:	endopeptidase inhibitor activity identical protein binding binding protein binding serine-type endopeptidase inhibitor activity zinc ion binding heparin binding metal ion binding iron ion binding copper ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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