2b54

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Image:2b54.png

Template:STRUCTURE 2b54

Human cyclin dependent kinase 2 (CKD2)complexed with DIN-232305

Template:ABSTRACT PUBMED 15537345

About this Structure

2B54 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Markwalder JA, Arnone MR, Benfield PA, Boisclair M, Burton CR, Chang CH, Cox SS, Czerniak PM, Dean CL, Doleniak D, Grafstrom R, Harrison BA, Kaltenbach RF 3rd, Nugiel DA, Rossi KA, Sherk SR, Sisk LM, Stouten P, Trainor GL, Worland P, Seitz SP. Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of cyclin-dependent kinases. J Med Chem. 2004 Nov 18;47(24):5894-911. PMID:15537345 doi:10.1021/jm020455u

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